Anti-MSH6 Rabbit Monoclonal Antibody

Anti-MSH6 Rabbit Monoclonal Antibody
Anti-MSH6 Rabbit Monoclonal Antibody
Anti-MSH6 Rabbit Monoclonal Antibody
Anti-MSH6 Rabbit Monoclonal Antibody
Anti-MSH6 Rabbit Monoclonal Antibody
Anti-MSH6 Rabbit Monoclonal Antibody

Anti-MSH6 Rabbit Monoclonal Antibody

Rabbit IgG Monoclonal for MSH6 detection, Test with WB, IHC-F, IHC-P, ICC/IF in Human, Mouse, Rat

Reactivity
  • Human
  • Mouse
  • Rat
Application
  • WB
  • IHC-F
  • IHC-P
  • ICC
  • IF
Host
  • Rabbit
Catalog Number
    ABXB60436
$370.00

Shipping To:
United States

Product Information

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Target
    MSH6
Host
  • Rabbit
Storage
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
  • Monoclonal
Clone Number
    R05-2B5
Isotype
    IgG
Reactivity
  • Human
  • Mouse
  • Rat
Application
  • WB
  • IHC-F
  • IHC-P
  • ICC
  • IF
Application Details
    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
Immunogen
    A synthetic peptide of human MSH6
Molecular Weight
    Calculated MW: 153 kDa; Observed MW: 163 kDa
Formulation
    50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Form
    Liquid
Gene ID
    2956
Uniprot ID
    P52701
Background
    The DNA mismatch repair system (MMR) repairs post-replication DNA, inhibits recombination between nonidentical DNA sequences, and induces both checkpoint and apoptotic responses following certain types of DNA damage. MSH2 (MutS homologue 2) forms the hMutS-α dimer with MSH6 and is an essential component of the mismatch repair process.
Research Area
    Epigenetics and Nuclear Signaling
Synonyms
    MSH6; GTBP; DNA mismatch repair protein Msh6; hMSH6; G/T mismatch-binding protein; GTBP; GTMBP; MutS-alpha 160 kDa subunit; p160
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Product Image

Western blot analysis of MSH6 in K562, C6, 3T3, Hela lysates using MSH6 antibody.
Immunocytochemistry analysis of MSH6(green) in Hela using MSH6 antibody,and DAPI(blue)
Immunohistochemistry analysis of paraffin-embedded Human tonsil using MSH6 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.