Anti-MSH6 Mouse Monoclonal Antibody

Anti-MSH6 Mouse Monoclonal Antibody
Anti-MSH6 Mouse Monoclonal Antibody

Anti-MSH6 Mouse Monoclonal Antibody

Mouse IgG2a Monoclonal for MSH6 detection, Test with IHC-P in Human

Reactivity
  • Human
Application
  • IHC-P
Host
  • Mouse
Catalog Number
    ABXB00240
$400.00

Shipping To:
United States

Product Information

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Target
    MSH6
Host
  • Mouse
Storage
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
  • Monoclonal
Clone Number
    7H4-4C1-9C5
Isotype
    IgG2a
Reactivity
  • Human
Application
  • IHC-P
Application Details
    IHC: 1/100-1/500
Immunogen
    Synthesized peptide derived from human MutS Protein Homolog 6(MSH6)
Molecular Weight
    -
Formulation
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
    Liquid
Gene ID
    2956
Uniprot ID
    P52701
Background
    The DNA mismatch repair system (MMR) repairs post-replication DNA, inhibits recombination between nonidentical DNA sequences, and induces both checkpoint and apoptotic responses following certain types of DNA damage. MSH2 (MutS homologue 2) forms the hMutS-α dimer with MSH6 and is an essential component of the mismatch repair process.
Research Area
    Epigenetics and Nuclear Signaling
Synonyms
    MSH6; GTBP; DNA mismatch repair protein Msh6; hMSH6; G/T mismatch-binding protein; GTBP; GTMBP; MutS-alpha 160 kDa subunit; p160
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Immunohistochemistry analysis of paraffin-embedded Colon carcinoma using MSH6.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.