Anti-MonoMethyl-Histone H2B (Lys116) Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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H2BC21
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R96-4G-1
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/100-1/200 IF: 1/50-1/200
Immunogen
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A synthesized peptide derived from human Histone H2B (mono methyl K116)
Molecular Weight
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Calculated MW: 14kDa;Observed MW:14kDa
Formulation
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Liquid in PBS , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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8349
Uniprot ID
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Q16778
Background
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Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Research Area
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Epigenetics and Nuclear Signaling
Synonyms
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Histone H2B;