Anti-Mitofusin 1 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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MFN1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IF: 1/50-1/200
Immunogen
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Recombinant protein of human MFN1 (NP_284941.2).
Molecular Weight
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Calculated MW: 84 kDa; Observed MW: 84 kDa
Formulation
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Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
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Liquid
Gene ID
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55669
Uniprot ID
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Q8IWA4
Background
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Mitofusins are mitochondrial transmembrane GTPases that function to regulate mitochondrial fusion, a process that occurs in concert with mitochondrial division and is necessary for the maintenance of structural and genetic mitochondrial integrity. Two mitofusins have been described in mammals, mitofusin-1 and -2, which share 60% amino acid identity and appear to function coordinately to regulate mitochondrial fusion.
Research Area
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Neuroscience
Synonyms
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MFN1,Mitofusin-1,Fzo homolog,Transmembrane GTPase MFN1