Anti-Mitofusin 1 Mouse Monoclonal Antibody
Product Information
Downloads & Supports
Target
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MFN1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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4P2-T8-G7
Isotype
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IgG2a/Kappa
Reactivity
Application
Application Details
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WB:1/500-1/1000 IHC-P:1/50-1/100
Immunogen
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Peptide
Molecular Weight
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Calculated MW: 84 kDa; Observed MW:84 kDa
Formulation
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Liquid in PBS, Glycerol and BSA
Form
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Liquid
Gene ID
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55669
Uniprot ID
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Q8IWA4
Background
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Mitochondrial outer membrane GTPase that mediates mitochondrial clustering and fusion. Membrane clustering requires GTPase activity. It may involve a major rearrangement of the coiled coil domains. Mitochondria are highly dynamic organelles, and their morphology is determined by the equilibrium between mitochondrial fusion and fission events. Overexpression induces the formation of mitochondrial networks (in vitro). Has low GTPase activity.
Research Area
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Cell Biology
Synonyms
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MFN1,Mitofusin-1,Fzo homolog,Transmembrane GTPase MFN1