Anti-MICB Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
-
MICB
Host
Storage
-
Store at -20°C to -80°C for 12 months in lyophilized form.
Clonality
Clone Number
-
R04-2X-2
Isotype
-
IgG
Reactivity
Application
Application Details
-
FC: 1/50-1/100 ELISA: 1/10000
Immunogen
-
Recombinant human MICB protein
Molecular Weight
-
-
Formulation
-
Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Form
-
Lyophilized
Gene ID
-
4277
Uniprot ID
-
Q29980
Background
-
This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules; however, it does not associate with beta-2-microglobulin or bind peptides. Alternative splicing results in multiple transcript variants.
Research Area
-
Immunology
Synonyms
-
MIC-B; PERB11.2