Anti-MGMT Mouse Monoclonal Antibody

Anti-MGMT Mouse Monoclonal Antibody
Anti-MGMT Mouse Monoclonal Antibody
Anti-MGMT Mouse Monoclonal Antibody
Anti-MGMT Mouse Monoclonal Antibody

Anti-MGMT Mouse Monoclonal Antibody

Mouse IgG1 Monoclonal for MGMT detection, Test with IHC-P in Human

Reactivity
  • Human
Application
  • IHC-P
Host
  • Mouse
Catalog Number
    ABXB00358
$400.00

Shipping To:
United States

Product Information

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Target
    MGMT
Host
  • Mouse
Storage
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
  • Monoclonal
Clone Number
    ZN52
Isotype
    IgG1
Reactivity
  • Human
Application
  • IHC-P
Application Details
    IHC: 1/50-1/100
Immunogen
    Full length human recombinant protein of human MGMT (NP_002403) produced in E.coli.
Molecular Weight
    -
Formulation
    PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Form
    Liquid
Gene ID
    4255
Uniprot ID
    P16455
Background
    MGMT (O-6-methylguanine-DNA methyltransferase) is a DNA repair enzyme that participates in a suicide reaction that specifically removes methyl or alkyl groups from the O(6) position of guanine, restoring guanine to its normal form without causing DNA breaks. MGMT protects cells from alkylating toxins, and is an important factor in drug resistance to alkylating therapeutic agents.
Research Area
    Epigenetics and Nuclear Signaling
Synonyms
    Methylated-DNA--protein-cysteine methyltransferase;6-O-methylguanine-DNA methyltransferase (MGMT);O-6-methylguanine-DNA-alkyltransferase
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Product Image

Immunohistochemistry analysis of paraffin-embedded Human lung Carcinoma using MGMT antibbody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
Immunohistochemistry analysis of paraffin-embedded Human thyroid tissue using MGMT antibbody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.