Anti-mGluR1 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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GRM1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100
Immunogen
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Synthetic peptide of human GRM1
Molecular Weight
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Calculated MW: 132 kDa; Observed MW: 132 kDa
Formulation
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pH 7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
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Liquid
Gene ID
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2911
Uniprot ID
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Q13255
Background
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L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties.
Research Area
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Neuroscience
Synonyms
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GRM1; GPRC1A; MGLUR1; Metabotropic glutamate receptor 1; mGluR1