Anti-Metalloproteinase Inhibitor 3 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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TIMP3
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100
Immunogen
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Fusion protein of human TIMP3
Molecular Weight
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Calculated MW: 24 kDa; Observed MW: 24 kDa
Formulation
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pH 7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
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Liquid
Gene ID
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7078
Uniprot ID
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P35625
Background
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This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix (ECM). Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy.
Research Area
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Signal Transduction
Synonyms
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SFD; K222; K222TA2; HSMRK222