Anti-Melanocyte Protein PMEL Mouse Monoclonal Antibody
Product Information
Downloads & Supports
Target
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PMEL
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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6G4-6F1-2H10
Isotype
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IgG2b
Reactivity
Application
Application Details
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IHC: 1/100-1/500
Immunogen
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Synthesized peptide derived from human PMEL
Molecular Weight
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-
Formulation
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Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
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Liquid
Gene ID
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6490
Uniprot ID
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P40967
Background
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Plays a central role in the biogenesis of melanosomes. Involved in the maturation of melanosomes from stage I to II. The transition from stage I melanosomes to stage II melanosomes involves an elongation of the vesicle, and the appearance within of distinct fibrillar structures. Release of the soluble form, ME20-S, could protect tumor cells from antibody mediated immunity.
Research Area
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Tags & Cell Markers
Synonyms
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PMEL; ME20-M; Premelanosome protein; Silver locus protein homolog; PMEL17; SILV