Anti-MCM5 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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MCM5
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R09-5B-1
Isotype
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IgG/Kappa
Reactivity
Application
Application Details
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WB：1/500-1/1000，IHC-P：1/50-1/100，ICC/IF：1/50
Immunogen
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Peptide
Molecular Weight
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Calculated MW: 82 kDa; Observed MW:82 kDa
Formulation
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Liquid in PBS, Glycerol and BSA
Form
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Liquid
Gene ID
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4174
Uniprot ID
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P33992
Background
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Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Interacts with MCMBP.
Research Area
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Metabolomics
Synonyms
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CDC46