Anti-MCM2 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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MCM2
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R09-4F-7
Isotype
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IgG
Reactivity
Application
Application Details
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IHC-P：1/50-1/100
Immunogen
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Peptide
Molecular Weight
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Calculated MW: 102 kDa; Observed MW:125 kDa
Formulation
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Liquid in PBS, Glycerol and BSA
Form
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Liquid
Gene ID
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4171
Uniprot ID
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P49736
Background
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Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit.
Research Area
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Epigenetics and Nuclear Signaling
Synonyms
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BM28, CCNL1, CDCL1