Anti-MBNL1 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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MBNL1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R02-4E4
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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A synthetic peptide of human MBNL1
Molecular Weight
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Calculated MW: 42 kDa; Observed MW: 42 kDa
Formulation
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50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Form
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Liquid
Gene ID
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4154
Uniprot ID
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Q9NR56
Background
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Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins.
Research Area
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Synonyms
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EXP; EXP35; EXP40; EXP42; MBNL; MBNL1