Anti-MAP4K4/NIK Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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MAP4K4
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R01-8L-9
Isotype
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IgG
Reactivity
Application
Application Details
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IHC: 1/100-1/200
Immunogen
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A synthesized peptide derived from human MAP4K4
Formulation
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Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
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Liquid
Gene ID
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9448
Uniprot ID
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O95819
Background
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Serine/threonine kinase that may play a role in the response to environmental stress and cytokines such as TNF-alpha. Appears to act upstream of the JUN N-terminal pathway. Phosphorylates SMAD1 on Thr-322.
Research Area
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Signal Transduction
Synonyms
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MAP4K4;HGK, KIAA0687, NIK;Mitogen-activated protein kinase kinase kinase kinase 4;HPK/GCK-like kinase HGK;MAPK/ERK kinase kinase kinase 4 (MEK kinase kinase 4; MEKKK 4);Nck-interacting kinase