Anti-MAGEA1 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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MAGEA1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R06-2L-5
Isotype
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IgG
Reactivity
Application
Application Details
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IHC: 1/100-1/200
Immunogen
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A synthesized peptide derived from human MAGEA1
Formulation
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Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
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Liquid
Gene ID
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4100
Uniprot ID
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P43355
Background
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May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.
Research Area
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Tags & Cell Markers
Synonyms
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MAGEA1;MAGE1, MAGE1A;Melanoma-associated antigen 1;Antigen MZ2-E;Cancer/testis antigen 1.1 (CT1.1);MAGE-1 antigen