Anti-Macro H2A.1 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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MACROH2A1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
Immunogen
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A synthesized peptide derived from human macroH2A.1
Molecular Weight
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Calculated MW: 40 kDa; Observed MW: 40 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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9555
Uniprot ID
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O75367
Background
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Involved in stable X chromosome inactivation. Inhibits the binding of transcription factors and interferes with the activity of remodeling SWI/SNF complexes. Inhibits histone acetylation by EP300 and recruits class I HDACs, which induces an hypoacetylated state of chromatin.
Research Area
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Epigenetics and Nuclear Signaling
Synonyms
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H2A.y; H2A/y; mH2A1; H2AF12M; MACROH2A1.1; macroH2A1.2