Anti-LTB4DH Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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PTGR1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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Synthetic peptide corresponding to Human LTB4DH.
Molecular Weight
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Calculated MW: 36kDa
Formulation
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1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Form
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Liquid
Gene ID
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22949
Uniprot ID
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Q14914
Background
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The NADP(H)-dependent enzyme leukotriene 12-hydroxy dehydrogenase (LTB4DH) catalyzes double bond reductions and oxo-reductions in lipoxins (15-oxo-lipoxin A 4 ), leukotrienes (leukotriene B 4) and E/F prostaglandins (15-oxo prostaglandins). The reactions mediated by LTB4DH constitute an important inactivation pathway for these key lipid mediators involved in inflammation. LTB4DH belongs to the medium-chain dehydrogenase/reductase enzyme family.
Research Area
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-
Synonyms
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Prostaglandin reductase 1; PRG-1; PRG1; 15-oxoprostaglandin 13-reductase; NADP-dependent leukotriene B4 12-hydroxydehydrogenase; PTGR1; LTB4DH