Anti-LIN28A (9G2) Mouse Monoclonal Antibody
Product Information
Downloads & Supports
Target
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LIN28A
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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9G2-5B6-1D1
Isotype
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IgG1
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IF: 1/50-1/200
Immunogen
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Purified recombinant fragment of LIN28 expressed in E. Coli.
Molecular Weight
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Calculated MW: 23 kDa; Observed MW: 23 kDa
Formulation
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Ascitic fluid containing 0.03% sodium azide.
Form
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Liquid
Gene ID
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79727
Uniprot ID
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Q9H9Z2
Background
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Involved in the timing of developmental events and choice of stage specific cell fates. Acts as a suppressor of microRNA (miRNA) biogenesis by specifically binding the precursor let-7 (pre-let-7), a miRNA precursor. Acts by binding pre-let-7 and recruiting ZCCHC11/TUT4 uridylyltransferase, leading to the terminal uridylation of pre-let-7.
Research Area
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Epigenetics and Nuclear Signaling
Synonyms
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CSDD1; FLJ12457; LIN 28; Lin-28A; LIN28; LIN28A; LN28A_HUMAN; Protein lin-28 homolog A; ZCCHC1; Zinc finger CCHC domain-containing protein 1.