Anti-LIN28 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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LIN28A/LIN28B
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R03-6H1
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IP: 1/50 FC: 1/50-1/100
Immunogen
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A synthesized peptide derived from human Lin28
Molecular Weight
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Calculated MW: 23 kDa; Observed MW: 26 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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79727/389421
Uniprot ID
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Q9H9Z2/Q6ZN17
Background
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Involved in the timing of developmental events and choice of stage specific cell fates. Acts as a suppressor of microRNA (miRNA) biogenesis by specifically binding the precursor let-7 (pre-let-7), a miRNA precursor. Acts by binding pre-let-7 and recruiting ZCCHC11/TUT4 uridylyltransferase, leading to the terminal uridylation of pre-let-7.
Research Area
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Neuroscience
Synonyms
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Protein lin-28 homolog A; LIN28A; CSDD1; LIN28; ZCCHC1