Anti-LIM Kinase 1 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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LIMK1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R07-7J4
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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A synthesized peptide derived from human LIM Kinase 1
Molecular Weight
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Calculated MW: 73 kDa; Observed MW: 73 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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3984
Uniprot ID
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P53667
Background
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Protein kinase which regulates actin filament dynamics. Phosphorylates and inactivates the actin binding/depolymerizing factor cofilin, thereby stabilizing the actin cytoskeleton. Stimulates axonal outgrowth and may be involved in brain development. Isoform 3 has a dominant negative effect on actin cytoskeletal changes.
Research Area
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Neuroscience
Synonyms
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LIMK1; LIMK; LIM domain kinase 1; LIMK-1