Anti-LGR5 Mouse Monoclonal Antibody

Anti-LGR5 Mouse Monoclonal Antibody
Anti-LGR5 Mouse Monoclonal Antibody
Anti-LGR5 Mouse Monoclonal Antibody
Anti-LGR5 Mouse Monoclonal Antibody

Anti-LGR5 Mouse Monoclonal Antibody

Mouse IgG2a Monoclonal for LGR5 detection, Test with IHC-P in Human

Reactivity
  • Human
Application
  • IHC-P
Host
  • Mouse
Catalog Number
    ABXB00390
$400.00

Shipping To:
United States

Product Information

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Target
    LGR5
Host
  • Mouse
Storage
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
  • Monoclonal
Clone Number
    ZN210
Isotype
    IgG2a
Reactivity
  • Human
Application
  • IHC-P
Application Details
    IHC: 1/50-1/100
Immunogen
    Human recombinant protein fragment of human LGR5 (NP_003658) produced in HEK293 cell.
Molecular Weight
    -
Formulation
    PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Form
    Liquid
Gene ID
    8549
Uniprot ID
    O75473
Background
    Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a stem cell marker of the intestinal epithelium and the hair follicle. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes.
Research Area
    Signal Transduction
Synonyms
    GPR49; GPR67; GRP49; LGR5
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Product Image

Immunohistochemistry analysis of paraffin-embedded human colon cancer using LGR5 antibbody. High-pressure and temperature was used for antigen retrieval.
Immunohistochemistry analysis of paraffin-embedded Human colon Adenocarcinoma using LGR5 antibbody. High-pressure and temperature Tris-EDTA pH 8.5 was used for antigen retrieval.