Anti-LDL Receptor Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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LDLR
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R04-3E7
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100
Immunogen
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A synthesized peptide derived from human LDL Receptor
Molecular Weight
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Calculated MW: 95 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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3949
Uniprot ID
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P01130
Background
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Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. In case of HIV-1 infection, functions as a receptor for extracellular Tat in neurons, mediating its internalization in uninfected cells.
Research Area
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Cardiovascular
Synonyms
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FH; FHC; LDL receptor; LDLCQ2; LDLR; Low Density Lipoprotein Receptor; Low density lipoprotein receptor class A domain containing protein 3