Anti-Lck (3E5) Mouse Monoclonal Antibody
Product Information
Downloads & Supports
Target
-
LCK
Host
Storage
-
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
3E5-C8-B9
Isotype
-
IgG1
Reactivity
Application
Application Details
-
WB: 1/500-1/1000
Immunogen
-
Purified recombinant human LCK protein fragments expressed in E.coli.
Molecular Weight
-
Calculated MW: 58 kDa; Observed MW: 58 kDa
Formulation
-
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
-
Liquid
Gene ID
-
3932
Uniprot ID
-
P06239
Background
-
The Src family of protein tyrosine kinases, which includes Src, Lyn, Fyn, Yes, Lck, Blk, and Hck, are important in the regulation of growth and differentiation of eukaryotic cells. Src activity is regulated by tyrosine phosphorylation at two sites, but with opposing effects.
Research Area
-
Immunology
Synonyms
-
LCK; Tyrosine-protein kinase Lck; Leukocyte C-terminal Src kinase; LSK; Lymphocyte cell-specific protein-tyrosine kinase; Protein YT16; Proto-oncogene Lck; T cell-specific protein-tyrosine kinase; p56-LCK