Anti-Lamin B Receptor Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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LBR
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20
Immunogen
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A synthesized peptide derived from human Lamin B Receptor
Molecular Weight
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Calculated MW: 71 kDa; Observed MW: 71 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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3930
Uniprot ID
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Q14739
Background
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The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.
Research Area
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Tags & Cell Markers
Synonyms
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PHA; LMN2R; TDRD18; DHCR14B; LBR