Anti-KMT4 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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DOT1L
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R03-1G7
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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A synthesized peptide derived from human KMT4 / Dot1L
Molecular Weight
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Calculated MW: 165 kDa; Observed MW: 185 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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84444
Uniprot ID
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Q8TEK3
Background
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Histone methyltransferase. Methylates 'Lys-79' of histone H3. Nucleosomes are preferred as substrate compared to free histones. Binds to DNA.
Research Area
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Epigenetics and Nuclear Signaling
Synonyms
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DOT 1; DOT1L; KMT4; Histone methyltransferase DOT1L; H3 lysine-79 specific