Anti-KIT(V560D Mutant) Mouse Monoclonal Antibody
Product Information
Downloads & Supports
Target
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C-Kit, CD117, KIT, PBT, SCFR
Host
Storage
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Store at -20°C. Avoid repeated freezing and thawing
Clonality
Clone Number
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3A1-J2-Y4
Isotype
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IgG
Reactivity
Application
Application Details
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ELISA: 1/1000-1/5000 WB: 1/500-1/1000
Immunogen
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A synthetic peptide from the internal region of KIT which includes the mutation of V560D, human origin.
Formulation
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PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Form
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Liquid
Uniprot ID
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Background
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Tyrosine-protein kinase Kit, also known as proto-oncogene c-Kit or CD117 or Mast/stem cell growth factor receptor (SCFR), is a receptor tyrosine kinase protein that in humans is encoded by the KIT gene. Activating mutations in this gene are associated with gastrointestinal stromal tumors, testicular seminoma, mast cell disease, melanoma, acute myeloid leukemia, while inactivating mutations are associated with the genetic defect piebaldism.
Research Area
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Immunology
Synonyms
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C-Kit, CD117, KIT, PBT, SCFR