Anti-KIT(V559D Mutant) Mouse Monoclonal Antibody

Anti-KIT(V559D Mutant) Mouse Monoclonal Antibody
Anti-KIT(V559D Mutant) Mouse Monoclonal Antibody

Anti-KIT(V559D Mutant) Mouse Monoclonal Antibody

Mouse IgG Monoclonal for C-Kit, CD117, KIT, PBT, SCFR detection, Test with WB, IHC-P, ELISA in Vertebrates

Reactivity
  • Vertebrates
Application
  • WB
  • IHC-P
  • ELISA
Host
  • Mouse
Catalog Number
    ABXB07348
$680.00

Shipping To:
United States

Product Information

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Target
    C-Kit, CD117, KIT, PBT, SCFR
Host
  • Mouse
Storage
    Store at -20°C. Avoid repeated freezing and thawing
Clonality
  • Monoclonal
Clone Number
    5Y2-Q6-A5
Isotype
    IgG
Reactivity
  • Vertebrates
Application
  • WB
  • IHC-P
  • ELISA
Application Details
    ELISA: 1/1000-1/5000 WB: 1/500-1/1000 IHC-P: 1/50-1/100
Immunogen
    A synthetic peptide from the internal region of KIT which includes the mutation of V559D, human origin.
Formulation
    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Form
    Liquid
Uniprot ID
    ­
Background
    Tyrosine-protein kinase Kit, also known as proto-oncogene c-Kit or CD117 or Mast/stem cell growth factor receptor (SCFR), is a receptor tyrosine kinase protein that in humans is encoded by the KIT gene. Activating mutations in this gene are associated with gastrointestinal stromal tumors, testicular seminoma, mast cell disease, melanoma, acute myeloid leukemia, while inactivating mutations are associated with the genetic defect piebaldism.
Research Area
    Immunology
Synonyms
    C-Kit, CD117, KIT, PBT, SCFR
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Product Image

Immunofluorescence of cells expressing KIT proteins with Anti-KIT(V559D). HEK293T cells were transfected with pCDNA3-GFP-KIT (WT) plasmid (left column) or pCDNA3-GFP-KIT(V559D) plasmid (right column), then fixed and stained with Anti-KIT(V559D) monoclonal.