Anti-JAK2 (7H5) Mouse Monoclonal Antibody

Anti-JAK2 (7H5) Mouse Monoclonal Antibody
Anti-JAK2 (7H5) Mouse Monoclonal Antibody
Anti-JAK2 (7H5) Mouse Monoclonal Antibody
Anti-JAK2 (7H5) Mouse Monoclonal Antibody

Anti-JAK2 (7H5) Mouse Monoclonal Antibody

Mouse IgG1 Monoclonal for JAK2 detection, Test with IHC-P in Human, Rat, Mouse

Reactivity
  • Human
  • Rat
  • Mouse
Application
  • IHC-P
Host
  • Mouse
Catalog Number
    ABXB05996
$370.00

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United States

Product Information

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Target
    JAK2
Host
  • Mouse
Storage
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
  • Monoclonal
Clone Number
    7H5-1H1-5D10
Isotype
    IgG1
Reactivity
  • Human
  • Rat
  • Mouse
Application
  • IHC-P
Application Details
    IHC: 1/50-1/100
Immunogen
    Synthetic peptide conjugated to KLH.
Molecular Weight
    -
Formulation
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
    Liquid
Gene ID
    3717
Uniprot ID
    O60674
Background
    Phosphorylated STATs then form homodimer or heterodimers and translocate to the nucleus to activate gene transcription. For example, cell stimulation with erythropoietin (EPO) during erythropoiesis leads to JAK2 autophosphorylation, activation, and its association with erythropoietin receptor (EPOR) that becomes phosphorylated in its cytoplasmic domain. Then, STAT5 (STAT5A or STAT5B) is recruited, phosphorylated and activated by JAK2.
Research Area
    Cell Biology
Synonyms
    JAK2; Tyrosine-protein kinase JAK2; Janus kinase 2; JAK-2
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Product Image

Immunohistochemistry analysis of paraffin-embedded Human Lung Carcinoma Tissue using JAK2 (7H5).High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
Immunohistochemical analysis of paraffin-embedded Human tonsils using JAK2 (7H5).High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.