Anti-Islet 1 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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ISL1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20 FC: 1/50-1/100
Immunogen
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A synthetic peptide of human Islet 1
Molecular Weight
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Calculated MW: 39 kDa; Observed MW: 39 kDa
Formulation
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50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Form
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Liquid
Gene ID
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3670
Uniprot ID
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P61371
Background
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ISL1 (ISL1 transcription factor, LIM/homeodomain) is a member of the LIM/homeodomain family of transcription factors. It binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. It is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Islet-1 expression defines cardiac progenitor cell populations and is required for normal cardiac development and asymmetry.
Research Area
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Neuroscience
Synonyms
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ISL1; Insulin gene enhancer protein ISL-1; Islet-1