Anti-IRF5 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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IRF5
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R06-8I2
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100 FC: 1/50-1/100
Immunogen
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A synthesized peptide derived from human IRF5
Molecular Weight
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Calculated MW: 56 kDa; Observed MW: 56 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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3663
Uniprot ID
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Q13568
Background
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Play an important role in pathogen defense, autoimmunity, lymphocyte development, cell growth, and susceptibility to transformation. Studies have shown that genetic variants of IRF-5 have been associated with disorders where the IFN pathway is abnormally activated, such as systemic lupus erythematosus.
Research Area
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Immunology
Synonyms
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Interferon regulatory factor 5; Interferon regulatory factor 5 bone marrow variant; IRF 5; SLEB10