Anti-IQGAP1 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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IQGAP1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R01-9S9
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 FC: 1/50-1/100
Immunogen
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A synthesized peptide derived from human IQGAP1
Molecular Weight
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Calculated MW: 189 kDa; Observed MW: 180 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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8826
Uniprot ID
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P46940
Background
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Binds to activated CDC42 but does not stimulate its GTPase activity. It associates with calmodulin. Could serve as an assembly scaffold for the organization of a multimolecular complex that would interface incoming signals to the reorganization of the actin cytoskeleton at the plasma membrane.
Research Area
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Signal Transduction
Synonyms
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IQGAP1; KIAA0051; Ras GTPase-activating-like protein IQGAP1; p195