Anti-Integrin beta 3 Mouse Monoclonal Antibody

Anti-Integrin beta 3 Mouse Monoclonal Antibody
Anti-Integrin beta 3 Mouse Monoclonal Antibody
Anti-Integrin beta 3 Mouse Monoclonal Antibody
Anti-Integrin beta 3 Mouse Monoclonal Antibody

Anti-Integrin beta 3 Mouse Monoclonal Antibody

Mouse IgG1 Monoclonal for ITGB3 detection, Test with IHC-P in Human

Reactivity
  • Human
Application
  • IHC-P
Host
  • Mouse
Catalog Number
    ABXB00228
$400.00

Shipping To:
United States

Product Information

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Target
    ITGB3
Host
  • Mouse
Storage
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
  • Monoclonal
Clone Number
    9H2-3D7-6D4
Isotype
    IgG1
Reactivity
  • Human
Application
  • IHC-P
Application Details
    IHC: 1/100-1/500
Immunogen
    Synthesized peptide derived from human CD61
Molecular Weight
    -
Formulation
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
    Liquid
Gene ID
    3690
Uniprot ID
    P05106
Background
    Integrin alpha-IIb/beta-3 recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial surface. Fibrinogen binding enhances SELP expression in activated platelets (By similarity).
Research Area
    Cardiovascular
Synonyms
    ITGB3; GP3A; Integrin beta-3; Platelet membrane glycoprotein IIIa; GPIIIa; CD antigen CD61
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Product Image

Immunohistochemistry analysis of paraffin-embedded Giantcell tumor of bone using Integrin beta 3.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
Immunohistochemistry analysis of paraffin-embedded Spleen using Integrin beta 3.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.