Anti-ING1 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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ING1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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Synthetic peptide of human ING1
Molecular Weight
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Calculated MW: 47 kDa; Observed MW: 47 kDa
Formulation
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pH 7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
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Liquid
Gene ID
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3621
Uniprot ID
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Q9UK53
Background
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This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.
Research Area
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Cell Biology
Synonyms
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p33; p47; p33ING1; p24ING1c; p33ING1b; p47ING1a