Anti-IL-8 (3A4) Mouse Monoclonal Antibody
Product Information
Downloads & Supports
Target
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CXCL8
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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3A4-8B3-7H1
Isotype
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IgG1
Reactivity
Application
Application Details
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IHC: 1/50-1/100
Immunogen
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Synthetic peptide conjugated to KLH.
Molecular Weight
-
-
Formulation
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Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
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Liquid
Gene ID
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3576
Uniprot ID
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P10145
Background
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IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively.
Research Area
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Immunology
Synonyms
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IL-8 (3A4); 9E3; CXCL8; CEF-4; GCP-1; Granulocyte chemotactic protein 1