Anti-IL-18 Receptor Accessory Protein Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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IL18RAP
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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IHC: 1/50-1/100 ELISA: 1/10000
Immunogen
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Synthetic peptide from human protein.
Molecular Weight
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-
Formulation
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Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
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Liquid
Gene ID
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8807
Uniprot ID
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O95256
Background
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Interleukin 18 receptor accessory protein, also known as IL18RAP and CDw218b (cluster of differentiationw218b), is a human gene. The protein encoded by this gene is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding activity of IL18R1 (IL1RRP), a ligand binding subunit of IL18 receptor. The coexpression of IL18R1 and this protein is required for the activation of NF-κB and MAPK8 (JNK) in response to IL18.
Research Area
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Immunology
Synonyms
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IL-18 Receptor Accessory Protein; ACPL; CD218b; IL18RB; CDw218b