Anti-IKB beta (3H3) Mouse Monoclonal Antibody
Product Information
Downloads & Supports
Target
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NFKBIB
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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3H3-6E9-9H9
Isotype
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IgG1
Reactivity
Application
Application Details
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IHC: 1/50-1/100
Immunogen
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Purified recombinant protein expressed in E.coli.
Molecular Weight
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-
Formulation
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Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
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Liquid
Gene ID
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4793
Uniprot ID
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Q15653
Background
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kB-beta a protein of the NF-kappa-B inhibitor family. Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further IKBA- dependent inactivation.
Research Area
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Signal Transduction
Synonyms
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NFKBIB; IKBB; TRIP9; NF-kappa-B inhibitor beta; NF-kappa-BIB; I-kappa-B-beta; IkB-B; IkB-beta; IkappaBbeta; Thyroid receptor-interacting protein 9; TR-interacting protein 9; TRIP-9