Anti-ICOS Ligand Mouse Monoclonal Antibody
Product Information
Downloads & Supports
Target
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ICOSLG
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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ZN254
Isotype
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IgG1
Reactivity
Application
Application Details
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IHC: 1/50-1/100
Immunogen
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Full length human recombinant protein of human ICOSLG (NP_056074) produced in HEK293T cell.
Molecular Weight
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-
Formulation
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PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Form
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Liquid
Gene ID
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23308
Uniprot ID
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O75144
Background
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Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function .
Research Area
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Immunology
Synonyms
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ICOS ligand; B7H2; GL50; B7-H2; B7RP1; CD275; ICOSL; B7RP-1; ICOS-L