Anti-Hydroxyacid Oxidase 1 Mouse Monoclonal Antibody
Product Information
Downloads & Supports
Target
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HAO1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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ZN117
Isotype
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IgG1
Reactivity
Application
Application Details
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IHC: 1/50-1/100
Immunogen
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Full length human recombinant protein of human HAO1 (NP_060015) produced in HEK293T cell.
Molecular Weight
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-
Formulation
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PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Form
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Liquid
Gene ID
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54363
Uniprot ID
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Q9UJM8
Background
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This gene is one of three related genes that have 2-hydroxyacid oxidase activity yet differ in encoded protein amino acid sequence, tissue expression and substrate preference. Subcellular location of the encoded protein is the peroxisome. Specifically, this gene is expressed primarily in liver and pancreas and the encoded protein is most active on glycolate, a two-carbon substrate. The protein is also active on 2-hydroxy fatty acids. The transcript detected at high levels in pancreas may represent an alternatively spliced form or the use of a multiple near-consensus upstream polyadenylation site. [provided by RefSeq, Jul 2008]
Research Area
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Tags & Cell Markers
Synonyms
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Glycolate oxidase; GOX1; HAOX1; 2-Hydroxyacid oxidase 1; Glycolate oxidase ; GOX