Anti-HuR Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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ELAVL1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/40 FC: 1/50-1/100
Immunogen
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A synthesized peptide derived from human HuR / ELAVL1
Molecular Weight
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Calculated MW: 36 kDa; Observed MW: 36 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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1994
Uniprot ID
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Q15717
Background
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Involved in 3'-UTR ARE-mediated MYC stabilization. Binds avidly to the AU-rich element in FOS and IL3/interleukin-3 mRNAs. In the case of the FOS AU-rich element, HUR binds to a core element of 27 nucleotides that contain AUUUA, AUUUUA and AUUUUUA motifs.
Research Area
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Epigenetics and Nuclear Signaling
Synonyms
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HUR; Hua; MelG; ELAV1