Anti-Human Anti-SARS CoV/CoV 2 NP
Product Information
Downloads & Supports
Target
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N
Host
Storage
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Store at 4°C for at least 6 months. Avoid freeze/thaw cycles
Clonality
Clone Number
-
-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IF: 1/50-1/200 FC: 1/50-1/100 ELISA: 1/10000
Immunogen
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A synthesized peptide derived from SARS CoV/CoV 2 NP
Molecular Weight
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Calculated MW: 46 kDa; Observed MW: 46 kDa
Formulation
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0.01M PBS, pH 7.2
Form
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Liquid
Gene ID
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43740575
Uniprot ID
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P0DTC9
Background
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Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. May induce inflammasome responses in cultured cells and mice. Acts by interacting with host NLRP3 to facilitate inflammasome assembly, which induces cytokine release that may play a role in COVID lung injury.
Research Area
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Infectious Diseases
Synonyms
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SARS CoV/CoV 2 NP; NC; Protein N