Anti-Hsp70 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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HSPA1A
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R04-7A2
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
Immunogen
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A synthetic peptide of human Hsp70
Molecular Weight
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Calculated MW: 70 kDa; Observed MW: 70 kDa
Formulation
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50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Form
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Liquid
Gene ID
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3303
Uniprot ID
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P0DMV8
Background
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In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins.
Research Area
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Signal Transduction
Synonyms
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HSP72; HSPA1; HSP70I; HSPA1B; HSP70-1; HSP70-1A.