Anti-HSD11B1 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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HSD11B1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R09-1F1
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100
Immunogen
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A synthesized peptide derived from human HSD11B1
Molecular Weight
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Calculated MW: 32 kDa; Observed MW: 32 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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3290
Uniprot ID
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P28845
Background
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Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone. Catalyzes reversibly the conversion of 7-ketocholesterol to 7-beta-hydroxycholesterol. In intact cells, the reaction runs only in one direction, from 7-ketocholesterol to 7-beta-hydroxycholesterol.
Research Area
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Signal Transduction
Synonyms
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11-DH; 11-beta-HSD1; HSD11B1; HSD11; HSD11L; 11 beta HSD1