Anti-HP1 gamma (6D8) Mouse Monoclonal Antibody
Product Information
Downloads & Supports
Target
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CBX3
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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6D8-10D10-5A9
Isotype
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IgG1
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100
Immunogen
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Purified recombinant protein expressed in E.coli.
Molecular Weight
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Calculated MW: 21 kDa; Observed MW: 24 kDa
Formulation
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Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
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Liquid
Gene ID
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11335
Uniprot ID
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Q13185
Background
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Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.
Research Area
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Epigenetics and Nuclear Signaling
Synonyms
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CBX3; Chromobox protein homolog 3; HECH; Heterochromatin protein 1 homolog gamma; HP1 gamma; Modifier 2 protein