Anti-HP1 alpha (1E8) Mouse Monoclonal Antibody

Anti-HP1 alpha (1E8) Mouse Monoclonal Antibody
Anti-HP1 alpha (1E8) Mouse Monoclonal Antibody
Anti-HP1 alpha (1E8) Mouse Monoclonal Antibody
Anti-HP1 alpha (1E8) Mouse Monoclonal Antibody
Anti-HP1 alpha (1E8) Mouse Monoclonal Antibody
Anti-HP1 alpha (1E8) Mouse Monoclonal Antibody
Anti-HP1 alpha (1E8) Mouse Monoclonal Antibody
Anti-HP1 alpha (1E8) Mouse Monoclonal Antibody
Anti-HP1 alpha (1E8) Mouse Monoclonal Antibody
Anti-HP1 alpha (1E8) Mouse Monoclonal Antibody

Anti-HP1 alpha (1E8) Mouse Monoclonal Antibody

Mouse IgG1 Monoclonal for CBX5 detection, Test with WB, IHC-P in Human, Rat, Mouse

Reactivity
  • Human
  • Rat
  • Mouse
Application
  • WB
  • IHC-P
Host
  • Mouse
Catalog Number
    ABXB06307
$370.00

Shipping To:
United States

Product Information

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Target
    CBX5
Host
  • Mouse
Storage
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
  • Monoclonal
Clone Number
    1E8-5C3-10E1
Isotype
    IgG1
Reactivity
  • Human
  • Rat
  • Mouse
Application
  • WB
  • IHC-P
Application Details
    WB: 1/500-1/1000 IHC: 1/50-1/100
Immunogen
    Purified recombinant protein expressed in E.coli.
Molecular Weight
    Calculated MW: 22 kDa; Observed MW: 22 kDa
Formulation
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
    Liquid
Gene ID
    23468
Uniprot ID
    P45973
Background
    Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.
Research Area
    Epigenetics and Nuclear Signaling
Synonyms
    CBX5; HP1A; Chromobox protein homolog 5; Antigen p25; Heterochromatin protein 1 homolog alpha; HP1 alpha
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Immunohistochemistry analysis of paraffin-embedded Human Colon Carcinoma Tissue using HP1 alpha (1E8).High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
Immunohistochemical analysis of paraffin-embedded Human tonsils using HP1 alpha (1E8).High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
Immunohistochemistry analysis of paraffin-embedded Human Placenta Tissue using HP1 alpha (1E8) High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
Western blot analysis of HP1 alpha (1E8) in COS7, Hela lysates using HP1 alpha (1E8).
Western blot analysis of HP1α in Hela, A549, HL-60, U2OS, C6 lysates using HP1 alpha (1E8)