Anti-HMGCL Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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HMGCL
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R08-7H5
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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A synthetic peptide of human HMGCL
Molecular Weight
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Calculated MW: 34 kDa; Observed MW: 34 kDa
Formulation
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50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Form
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Liquid
Gene ID
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3155
Uniprot ID
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P35914
Background
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Key enzyme in ketogenesis (ketone body formation). Terminal step in leucine catabolism. Ketone bodies (beta-hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism.
Research Area
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Signal Transduction
Synonyms
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3-hydroxymethyl-3-methylglutaryl-CoA lyase; HL