Anti-HMGB2 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
-
HMGB2
Host
Storage
-
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
-
Isotype
-
IgG
Reactivity
Application
Application Details
-
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20
Immunogen
-
A synthesized peptide derived from human HMGB2
Molecular Weight
-
Calculated MW: 24 kDa; Observed MW: 24 kDa
Formulation
-
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
-
Liquid
Gene ID
-
3148
Uniprot ID
-
P26583
Background
-
DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS).
Research Area
-
Epigenetics and Nuclear Signaling
Synonyms
-
HMG 2; HMG B2; HMG-2; HMG2; HMGB2