Anti-HMGB1 Rabbit Monoclonal Antibody

Anti-HMGB1 Rabbit Monoclonal Antibody
Anti-HMGB1 Rabbit Monoclonal Antibody
Anti-HMGB1 Rabbit Monoclonal Antibody
Anti-HMGB1 Rabbit Monoclonal Antibody

Anti-HMGB1 Rabbit Monoclonal Antibody

Rabbit IgG Monoclonal for HMGB1 detection, Test with WB, IHC-P in Human, Mouse, Rat

Reactivity
  • Human
  • Mouse
  • Rat
Application
  • WB
  • IHC-P
Host
  • Rabbit
Catalog Number
    ABXB62264
$370.00

Shipping To:
United States

Product Information

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Target
    HMGB1
Host
  • Rabbit
Storage
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
  • Monoclonal
Clone Number
    R07-2D8
Isotype
    IgG
Reactivity
  • Human
  • Mouse
  • Rat
Application
  • WB
  • IHC-P
Application Details
    WB: 1/500-1/1000 IHC: 1/50-1/100
Immunogen
    A synthetic peptide of human HMGB1
Molecular Weight
    Calculated MW: 25 kDa; Observed MW: 25 kDa
Formulation
    50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Form
    Liquid
Gene ID
    3146
Uniprot ID
    P09429
Background
    High mobility group (HMG) proteins 1 and 2 are ubiquitous non-histone components of chromatin. Evidence suggests that the binding of HMG proteins to DNA induces alterations in the DNA architecture including DNA bending and unwinding of the helix. HMG proteins synergize with Oct-2, members of the NFκB family, ATF-2 and c-Jun to activate transcription.
Research Area
    Epigenetics and Nuclear Signaling
Synonyms
    HMGB1; HMG1; High mobility group protein B1; High mobility group protein 1; HMG-1
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Product Image

Western blot analysis of HMGB1 in K562, rat Brain, C6, 3T3, Hela lysates using HMGB1 antibody.
Immunohistochemistry analysis of paraffin-embedded Human tonsil using HMGB1 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.