Anti-Histone H3 (10A10) Mouse Monoclonal Antibody
Product Information
Downloads & Supports
Target
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H3C1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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10A10-4H3-2A1
Isotype
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IgG1
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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Recombinant Protein of Histone H3
Molecular Weight
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Calculated MW: 15 kDa; Observed MW: 15 kDa
Formulation
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Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
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Liquid
Gene ID
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8350
Uniprot ID
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P68431
Background
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H3 Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.
Research Area
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Epigenetics and Nuclear Signaling
Synonyms
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H3 histone; family 3A; H3 histone; family 3B (H3.3B); H3.3A; H3.3B; H33; H3F3; H3F3A; H3F3B; Histone H3.3