Anti-Histone H2B (yeast) Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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HTB1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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A synthesized peptide derived from yeast Histone H2B (yeast)
Molecular Weight
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Calculated MW: 14 kDa; Observed MW: 14 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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851810
Uniprot ID
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P02293
Background
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Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Research Area
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Epigenetics and Nuclear Signaling
Synonyms
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HTB2; Htb2p; HTB1; Htb1p; Histone H2B.1; Histone H2B.2; SPT12