Anti-Histone H2B Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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H2BC12
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20 FC: 1/50-1/100
Immunogen
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A synthesized peptide derived from human Histone H2B
Molecular Weight
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Calculated MW: 14 kDa; Observed MW: 14 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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85236
Uniprot ID
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O60814
Background
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Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.
Research Area
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Epigenetics and Nuclear Signaling
Synonyms
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Histone H2B type 1-H; Histone H2B.j; H2B/j; HIST1H2BH; H2BFJ